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Gene: Grb7 (growth factor receptor bound protein 7) Rattus norvegicus
Symbol: Grb7
Name: growth factor receptor bound protein 7
Description: Predicted to have identical protein binding activity; phosphatidylinositol binding activity; and protein kinase binding activity. Predicted to be involved in negative regulation of translation; positive regulation of cell migration; and stress granule assembly. Predicted to localize to cytoplasmic stress granule; cytosol; and focal adhesion. Orthologous to human GRB7 (growth factor receptor bound protein 7); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: epidermal growth factor receptor GRB-7; GRB7 adapter protein; growth factor receptor binding protein GRB7; growth factor receptor-bound protein 7; MGC93307
Homo sapiens (human) : GRB7 (growth factor receptor bound protein 7)  HGNC  Alliance
Mus musculus (house mouse) : Grb7 (growth factor receptor bound protein 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb7 (growth factor receptor bound protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB7 (growth factor receptor bound protein 7)
Canis lupus familiaris (dog) : GRB7 (growth factor receptor bound protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb7 (growth factor receptor bound protein 7)
Sus scrofa (pig) : GRB7 (growth factor receptor bound protein 7)
Chlorocebus sabaeus (African green monkey) : GRB7 (growth factor receptor bound protein 7)
Heterocephalus glaber (naked mole-rat) : Grb7 (growth factor receptor bound protein 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01086,393,186 - 86,408,893 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,399,827 - 86,409,348 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,195,239 - 86,204,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,252,571 - 87,261,619 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,266,940 - 87,275,988 (+)NCBI
Celera1082,191,697 - 82,200,731 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Grb7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619759
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.