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Gene: Mcf2l (MCF.2 cell line derived transforming sequence-like) Rattus norvegicus
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Symbol: Mcf2l
Name: MCF.2 cell line derived transforming sequence-like
Description: Exhibits Rho guanyl-nucleotide exchange factor activity. Involved in positive regulation of Rho protein signal transduction. Localizes to the cytoplasm and extrinsic component of membrane. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DBL's big sister; guanine nucleotide exchange factor DBS; LOC100361711; mcf 2l; mcf.2 transforming sequence-like; MCF2-transforming sequence-like protein; Ost; OST oncogene
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01681,839,686 - 81,986,007 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,839,653 - 81,980,027 (-)Ensembl
Rnor_5.01681,325,603 - 81,471,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,365,090 - 81,469,766 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11681,365,289 - 81,386,688NCBI
Celera1674,314,419 - 74,419,162 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mcf2l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619782
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.