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Gene: Tnfrsf11b (TNF receptor superfamily member 11B) Rattus norvegicus
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Symbol: Tnfrsf11b
Name: TNF receptor superfamily member 11B
Description: Predicted to have cytokine activity. Involved in several processes, including negative regulation of bone resorption; negative regulation of odontogenesis of dentin-containing tooth; and response to magnesium ion. Localizes to extracellular space. Biomarker of congestive heart failure and myocarditis. Human ortholog(s) of this gene implicated in Paget's disease of bone and osteoarthritis. Orthologous to human TNFRSF11B (TNF receptor superfamily member 11b); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH (20S)-ginsenoside Rg3; (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93568; Opg; Osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Orthologs:
Homo sapiens (human) : TNFRSF11B (TNF receptor superfamily member 11b)  HGNC  Alliance
Mus musculus (house mouse) : Tnfrsf11b (tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf11b (TNF receptor superfamily member 11b)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF11B (TNF receptor superfamily member 11b)
Canis lupus familiaris (dog) : TNFRSF11B (TNF receptor superfamily member 11b)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf11b (TNF receptor superfamily member 11b)
Sus scrofa (pig) : TNFRSF11B (TNF receptor superfamily member 11b)
Chlorocebus sabaeus (African green monkey) : TNFRSF11B (TNF receptor superfamily member 11b)
Heterocephalus glaber (naked mole-rat) : Tnfrsf11b (TNF receptor superfamily member 11b)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0793,798,580 - 93,826,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl793,798,545 - 93,826,665 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0794,436,612 - 94,464,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4790,606,424 - 90,634,431 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1790,640,654 - 90,668,661 (-)NCBI
Celera782,388,596 - 82,416,602 (-)NCBICelera
Cytogenetic Map7q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tnfrsf11b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619802
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.