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Gene: Tjp2 (tight junction protein 2) Rattus norvegicus
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Symbol: Tjp2
Name: tight junction protein 2
Description: Exhibits protein C-terminus binding activity. Involved in response to organic substance. Localizes to bicellular tight junction. Biomarker of hypertension. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 51; disease of metabolism; and progressive familial intrahepatic cholestasis 4. Orthologous to human TJP2 (tight junction protein 2); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC124724; tight junction protein ZO-2; ZO-2
Orthologs:
Homo sapiens (human) : TJP2 (tight junction protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Tjp2 (tight junction protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tjp2 (tight junction protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TJP2 (tight junction protein 2)
Canis lupus familiaris (dog) : TJP2 (tight junction protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tjp2 (tight junction protein 2)
Sus scrofa (pig) : TJP2 (tight junction protein 2)
Chlorocebus sabaeus (African green monkey) : TJP2 (tight junction protein 2)
Heterocephalus glaber (naked mole-rat) : Tjp2 (tight junction protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01241,945,816 - 242,084,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,945,841 - 242,083,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,224,590 - 249,358,779 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,475,386 - 227,574,457 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,639,414 - 227,668,771 (-)NCBI
Celera1218,921,753 - 219,049,897 (-)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tjp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619807
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.