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Gene: Tnfsf4 (TNF superfamily member 4) Rattus norvegicus
Symbol: Tnfsf4
Name: TNF superfamily member 4
Description: Exhibits tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including T cell proliferation; positive regulation of activated T cell proliferation; and positive regulation of interleukin-2 production. Localizes to cell surface. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human TNFSF4 (TNF superfamily member 4); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
Also known as: OX40 ligand; Ox40l; Tnlg2b; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand 2b; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4
Homo sapiens (human) : TNFSF4 (TNF superfamily member 4)  HGNC  Alliance
Mus musculus (house mouse) : Tnfsf4 (tumor necrosis factor (ligand) superfamily, member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfsf4 (TNF superfamily member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF4 (TNF superfamily member 4)
Canis lupus familiaris (dog) : TNFSF4 (TNF superfamily member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf4 (TNF superfamily member 4)
Sus scrofa (pig) : TNFSF4 (TNF superfamily member 4)
Chlorocebus sabaeus (African green monkey) : TNFSF4 (TNF superfamily member 4)
Heterocephalus glaber (naked mole-rat) : Tnfsf4 (TNF superfamily member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01379,269,973 - 79,293,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1379,269,973 - 79,293,778 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01384,166,838 - 84,190,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41377,026,337 - 77,050,223 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11377,040,524 - 77,064,407 (+)NCBI
Celera1373,499,753 - 73,523,609 (+)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tnfsf4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619816
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.