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Gene: Serpina5 (serpin family A member 5) Rattus norvegicus
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Symbol: Serpina5
Name: serpin family A member 5
Description: Exhibits serine-type endopeptidase inhibitor activity. Involved in negative regulation of proteolysis and seminal vesicle development. Predicted to localize to several cellular components, including the cytoplasmic vesicle; protein C inhibitor-KLK3 complex; and protein C inhibitor-PLAT complex. Orthologous to human SERPINA5 (serpin family A member 5); PARTICIPATES IN fibrinolysis pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC93420; Pci; plasma serine protease inhibitor; protein C inhibitor; serine (or cysteine) peptidase inhibitor, clade A, member 5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serpin peptidase inhibitor, clade A, member 5
Orthologs:
Homo sapiens (human) : SERPINA5 (serpin family A member 5)  HGNC  Alliance
Mus musculus (house mouse) : Serpina5 (serine (or cysteine) peptidase inhibitor, clade A, member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpina5 (serpin family A member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINA5 (serpin family A member 5)
Canis lupus familiaris (dog) : LOC480424 (plasma serine protease inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpina5 (serpin family A member 5)
Sus scrofa (pig) : SERPINA5 (serpin family A member 5)
more info ...
Allele / Splice: Serpina5m1Mcwi  
Genetic Models: SS-Serpina5m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06127,753,152 - 127,772,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06136,972,583 - 136,990,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46128,156,901 - 128,161,334 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16128,160,647 - 128,165,080 (+)NCBI
Celera6120,503,068 - 120,508,038 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Serpina5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619817
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.