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Gene: Suclg1 (succinate-CoA ligase, alpha subunit) Rattus norvegicus
Symbol: Suclg1
Name: succinate-CoA ligase, alpha subunit
Description: Exhibits GDP binding activity; succinate-CoA ligase (ADP-forming) activity; and succinate-CoA ligase (GDP-forming) activity. Involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Localizes to the succinate-CoA ligase complex (GDP-forming). Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 9. Orthologous to human SUCLG1 (succinate-CoA ligase alpha subunit); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
Also known as: SCS-alpha; succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase, GDP-forming alpha subunit; succinate-CoA ligase, GDP-forming, alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase alpha subunit; succinyl-CoA synthetase subunit alpha
Homo sapiens (human) : SUCLG1 (succinate-CoA ligase alpha subunit)  HGNC  Alliance
Mus musculus (house mouse) : Suclg1 (succinate-CoA ligase, GDP-forming, alpha subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Suclg1 (succinate-CoA ligase alpha subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUCLG1 (succinate-CoA ligase alpha subunit)
Canis lupus familiaris (dog) : SUCLG1 (succinate-CoA ligase alpha subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Suclg1 (succinate-CoA ligase alpha subunit)
Sus scrofa (pig) : SUCLG1 (succinate-CoA ligase alpha subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04101,181,315 - 101,210,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4101,180,404 - 101,210,746 (+)Ensembl
Rnor_5.04165,937,922 - 165,967,277 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44106,572,140 - 106,601,495 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1836,133,697 - 36,137,263 (-)NCBI
Celera494,449,454 - 94,478,818 (+)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Suclg1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619821
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.