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Gene: Cttn (cortactin) Rattus norvegicus
Symbol: Cttn
Name: cortactin
CRRD ID: 619839
Description: Exhibits Arp2/3 complex binding activity and proline-rich region binding activity. Involved in several processes, including focal adhesion assembly; modification of postsynaptic actin cytoskeleton; and nervous system development. Localizes to clathrin-coated pit; glutamatergic synapse; and postsynaptic actin cytoskeleton. Colocalizes with several cellular components, including actin filament; focal adhesion; and growth cone. Orthologous to human CTTN (cortactin); PARTICIPATES IN E-cadherin signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cortactin isoform B; Cttnb; MGC93456; src substrate cortactin
Homo sapiens (human) : CTTN (cortactin)  HGNC  Alliance
Mus musculus (house mouse) : Cttn (cortactin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cttn (cortactin)
Pan paniscus (bonobo/pygmy chimpanzee) : CTTN (cortactin)
Canis lupus familiaris (dog) : CTTN (cortactin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cttn (cortactin)
Sus scrofa (pig) : CTTN (cortactin)
Chlorocebus sabaeus (African green monkey) : CTTN (cortactin)
Heterocephalus glaber (naked mole-rat) : Cttn (cortactin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01215,255,385 - 215,290,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01217,602,698 - 217,638,196 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,602,698 - 217,638,152 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,255,381 - 215,290,845 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,459,485 - 224,494,974 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01222,159,088 - 222,194,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,865,768 - 204,901,221 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11205,020,464 - 205,048,384 (-)NCBI
Celera1197,159,379 - 197,194,704 (-)NCBICelera
Cytogenetic Map1q41-q42NCBI
RH 3.4 Map11561.5RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cttn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619839
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.