Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gper1 (G protein-coupled estrogen receptor 1) Rattus norvegicus
Symbol: Gper1
Name: G protein-coupled estrogen receptor 1
Description: Exhibits several functions, including estrogen receptor activity; hormone binding activity; and steroid binding activity. Involved in several processes, including apoptotic nuclear changes; cellular response to lipid; and positive regulation of signal transduction. Localizes to several cellular components, including dendrite; postsynaptic density; and synaptic membrane. Orthologous to human GPER1 (G protein-coupled estrogen receptor 1); PARTICIPATES IN estrogen signaling pathway; bisphenol A response pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH (S)-amphetamine; 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol.
Type: protein-coding
Also known as: chemoattractant receptor-like 2; chemokine receptor-like 2; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; G-protein coupled receptor 41; Gper; Gpr30; GPR41; membrane estrogen receptor; mER
Homo sapiens (human) : GPER1 (G protein-coupled estrogen receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Gper1 (G protein-coupled estrogen receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gper1 (G protein-coupled estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100967334 (G-protein coupled estrogen receptor 1)
Canis lupus familiaris (dog) : GPER1 (G protein-coupled estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gper1 (G protein-coupled estrogen receptor 1)
Sus scrofa (pig) : GPER1 (G protein-coupled estrogen receptor 1)
Chlorocebus sabaeus (African green monkey) : GPER1 (G protein-coupled estrogen receptor 1)
Heterocephalus glaber (naked mole-rat) : Gper1 (G protein-coupled estrogen receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01217,309,122 - 17,315,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,309,834 - 17,311,112 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01219,296,086 - 19,301,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41215,718,615 - 15,719,893 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11215,748,542 - 15,749,821 (-)NCBI
Celera1216,971,703 - 16,972,981 (-)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Gper1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619845
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.