Gene: Gper1 (G protein-coupled estrogen receptor 1) Rattus norvegicus
Symbol: Gper1
Name: G protein-coupled estrogen receptor 1
Description: Exhibits several functions, including drug binding activity, estrogen receptor activity, and hormone binding activity; involved in several processes, including apoptotic nuclear changes, cellular response to hormone stimulus, and positive regulation of signal transduction; localizes to several cellular components, including the cytoplasm, neuron projection, and postsynaptic density; orthologous to human GPER1 (G protein-coupled estrogen receptor 1); PARTICIPATES IN estrogen signaling pathway; bisphenol A response pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH (S)-amphetamine; 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol.
Type: protein-coding
Also known as: chemoattractant receptor-like 2; chemokine receptor-like 2; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; G-protein coupled receptor 41; Gper; Gpr30; GPR41; membrane estrogen receptor; mER
Homo sapiens (human) : GPER1 (G protein-coupled estrogen receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Gper1 (G protein-coupled estrogen receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gper1 (G protein-coupled estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPER1 (G protein-coupled estrogen receptor 1)
Canis lupus familiaris (dog) : GPER1 (G protein-coupled estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gper1 (G protein-coupled estrogen receptor 1)
Sus scrofa (pig) : GPER1 (G protein-coupled estrogen receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01217,309,122 - 17,315,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01219,296,086 - 19,301,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41215,718,615 - 15,719,893 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11215,748,542 - 15,749,821 (-)NCBI
Celera1216,971,703 - 16,972,981 (-)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Gper1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619845
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.