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Gene: Serpind1 (serpin family D member 1) Rattus norvegicus
Symbol: Serpind1
Name: serpin family D member 1
CRRD ID: 619854
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in heparin cofactor II deficiency. Orthologous to human SERPIND1 (serpin family D member 1); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: HC-II; heparin cofactor 2; heparin cofactor II; leuserpin 2; leuserpin-2; protease inhibitor leuserpin-2; rls2var1; serine (or cysteine) peptidase inhibitor, clade D, member 1; serine (or cysteine) proteinase inhibitor, clade D, member 1; serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Homo sapiens (human) : SERPIND1 (serpin family D member 1)  HGNC  Alliance
Mus musculus (house mouse) : Serpind1 (serine (or cysteine) peptidase inhibitor, clade D, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpind1 (serpin family D member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPIND1 (serpin family D member 1)
Canis lupus familiaris (dog) : SERPIND1 (serpin family D member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpind1 (serpin family D member 1)
Sus scrofa (pig) : SERPIND1 (serpin family D member 1)
Chlorocebus sabaeus (African green monkey) : SERPIND1 (serpin family D member 1)
Heterocephalus glaber (naked mole-rat) : Serpind1 (serpin family D member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01187,913,814 - 87,924,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,913,806 - 87,924,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,969,513 - 90,980,577 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,666,714 - 85,677,716 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,707,310 - 85,718,313 (-)NCBI
Celera1182,428,108 - 82,439,110 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Serpind1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619854
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.