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Gene: Nme2 (NME/NM23 nucleoside diphosphate kinase 2) Rattus norvegicus
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Symbol: Nme2
Name: NME/NM23 nucleoside diphosphate kinase 2
Description: Exhibits several functions, including fatty acid binding activity; intermediate filament binding activity; and kinase activity. Involved in several processes, including cellular response to glucose stimulus; nucleotide metabolic process; and response to growth hormone. Localizes to the mitochondrial membrane and perinuclear region of cytoplasm. Colocalizes with the intermediate filament. Human ortholog(s) of this gene implicated in teratoma. Orthologous to several human genes including NME2 (NME/NM23 nucleoside diphosphate kinase 2); PARTICIPATES IN adefovir pharmacokinetics pathway; de novo pyrimidine biosynthetic pathway; Glut1 deficiency syndrome pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-azacytidine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: expressed in non-metastatic cells 2; histidine protein kinase NDKB; NDK B; NDKB; NDP kinase alpha; NDP kinase B; nm23-2; non-metastatic cells 2, protein (NM23B) expressed in; nucleoside diphosphate kinase; nucleoside diphosphate kinase B; P18; p18-12d
Orthologs:
Related Pseudogenes: Nme2-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01081,648,216 - 81,653,717 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01081,478,178 - 81,483,679 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41082,582,766 - 82,588,269 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11082,597,135 - 82,602,639 (-)NCBI
Celera1077,694,496 - 77,700,026 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nme2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619877
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.