Gene: Braf (B-Raf proto-oncogene, serine/threonine kinase) Rattus norvegicus
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Symbol: Braf
Name: B-Raf proto-oncogene, serine/threonine kinase
Description: Exhibits MAP kinase kinase kinase activity, enzyme binding activity, and protein heterodimerization activity; involved in several processes, including cellular response to nerve growth factor stimulus, negative regulation of neuron apoptotic process, and positive regulation of ERK1 and ERK2 cascade; localizes to the neuron projection, nucleus, and plasma membrane; orthologous to human BRAF (B-Raf proto-oncogene, serine/threonine kinase); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; adenosine signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: MODEL
Also known as: B-Raf; serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Orthologs:
Homo sapiens (human) : BRAF (B-Raf proto-oncogene, serine/threonine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Braf (Braf transforming gene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Braf (B-Raf proto-oncogene, serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : BRAF (B-Raf proto-oncogene, serine/threonine kinase)
Canis lupus familiaris (dog) : BRAF (B-Raf proto-oncogene, serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Braf (B-Raf proto-oncogene, serine/threonine kinase)
Sus scrofa (pig) : BRAF (B-Raf proto-oncogene, serine/threonine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0467,389,331 - 67,520,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0467,196,477 - 67,327,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4467,117,759 - 67,243,058 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1467,405,110 - 67,426,026 (-)NCBI
Celera463,383,337 - 63,515,499 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links