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Gene: Sorl1 (sortilin related receptor 1) Rattus norvegicus
Symbol: Sorl1
Name: sortilin related receptor 1
CRRD ID: 619914
Description: Predicted to have several functions, including ADP-ribosylation factor binding activity; low-density lipoprotein particle binding activity; and peptide binding activity. Involved in cell migration and cell population proliferation. Localizes to multivesicular body and neuronal cell body. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human SORL1 (sortilin related receptor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
Also known as: LDLR relative with 11 ligand-binding repeats; LOC300652; low-density lipoprotein receptor relative with 11 ligand-binding repeats; Lr11; RGD619914; similar to sortilin-related receptor, LDLR class A repeats-containing; SorLA; sortilin-related receptor; sortilin-related receptor, L(DLR class) A repeats-containing; sortilin-related receptor, LDLR class A repeats-containing; sorting protein-related receptor containing LDLR class A repeats
Homo sapiens (human) : SORL1 (sortilin related receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Sorl1 (sortilin-related receptor, LDLR class A repeats-containing)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sorl1 (sortilin related receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SORL1 (sortilin related receptor 1)
Canis lupus familiaris (dog) : SORL1 (sortilin related receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sorl1 (sortilin related receptor 1)
Sus scrofa (pig) : SORL1 (sortilin related receptor 1)
Chlorocebus sabaeus (African green monkey) : SORL1 (sortilin related receptor 1)
Heterocephalus glaber (naked mole-rat) : Sorl1 (sortilin related receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0846,228,077 - 46,287,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0844,702,383 - 44,872,500 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4844,962,730 - 45,101,843 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1844,971,645 - 45,214,890 (-)NCBI
Celera841,934,828 - 42,097,222 (-)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sorl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619914
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.