Gene: Rhoa (ras homolog family member A) Rattus norvegicus
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Symbol: Rhoa
Name: ras homolog family member A
Description: Exhibits several functions, including GTPase activity, Rho GDP-dissociation inhibitor binding activity, and anion binding activity; involved in several processes, including generation of neurons, intracellular signal transduction, and positive regulation of cell death; localizes to the axon, cytosol, and membrane; predicted to colocalize with the cleavage furrow; used to study membranous glomerulonephritis; biomarker of asthma, hypertension, obesity, and pulmonary hypertension; orthologous to human RHOA (ras homolog family member A); PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; E-cadherin signaling pathway; eicosanoid signaling pathway; INTERACTS WITH (-)-perillyl alcohol; (2-trans,6-trans)-farnesol; (R)-mevalonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Arha; Arha2; MGC72339; plysia ras-related homolog A2; ras homolog gene family, member A; transforming protein RhoA
Orthologs:
Homo sapiens (human) : RHOA (ras homolog family member A)  HGNC  Alliance
Mus musculus (house mouse) : Rhoa (ras homolog family member A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhoa (ras homolog family member A)
Pan paniscus (bonobo/pygmy chimpanzee) : RHOA (ras homolog family member A)
Canis lupus familiaris (dog) : RHOA (ras homolog family member A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhoa (ras homolog family member A)
Sus scrofa (pig) : RHOA (ras homolog family member A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,082,440 - 117,116,244 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,431,244 - 116,464,932 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,319,010 - 108,327,586 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Rhoa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619921
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.