Gene: Madd (MAP-kinase activating death domain) Rattus norvegicus
Analyze
Symbol: Madd
Name: MAP-kinase activating death domain
Description: Exhibits Rab guanyl-nucleotide exchange factor activity; involved in negative regulation of growth hormone secretion and negative regulation of pancreatic amylase secretion; localizes to the cytosol, nucleus, and synaptic vesicle; biomarker of transient cerebral ischemia; orthologous to human MADD (MAP kinase activating death domain); PARTICIPATES IN ceramide signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MAP kinase-activating death domain protein; rab3 GDP/GTP exchange factor; Rab3 GDP/GTP exchange protein
Orthologs:
Homo sapiens (human) : MADD (MAP kinase activating death domain)  HGNC  Alliance
Mus musculus (house mouse) : Madd (MAP-kinase activating death domain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Madd (MAP kinase activating death domain)
Pan paniscus (bonobo/pygmy chimpanzee) : MADD (MAP kinase activating death domain)
Canis lupus familiaris (dog) : MADD (MAP kinase activating death domain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Madd (MAP kinase activating death domain)
Sus scrofa (pig) : MADD (MAP kinase activating death domain)
more info ...
Allele / Splice: Maddm1Mcwi  
Genetic Models: FHH-Maddm1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0379,960,301 - 80,003,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0386,669,054 - 86,711,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,498,321 - 75,541,073 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,408,586 - 75,437,445 (-)NCBI
Celera376,323,258 - 76,366,073 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Madd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619922
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.