Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cyp2c6v1 (cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1) Rattus norvegicus
Analyze
Symbol: Cyp2c6v1
Name: cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
Description: Predicted to have enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to drug. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in eosinophilic esophagitis; multiple myeloma; and sickle cell anemia. Orthologous to human CYP2C19 (cytochrome P450 family 2 subfamily C member 19); PARTICIPATES IN carbamazepine pharmacokinetics pathway; citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; INTERACTS WITH 1,2-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2c6; CYPIIC6; cytochrome P450 2C6; cytochrome P450 PB1; cytochrome P450, family 2, subfamily c, polypeptide 6; cytochrome P450, family 2, subfamily C, polypeptide 6-like; cytochrome P450, subfamily IIC6; cytochrome P450-like; LOC246070; LOC293989; MGC109053; PB1; PTF2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01147,713,879 - 147,814,410 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01153,451,394 - 153,454,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01154,005,928 - 154,103,310 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,859,015 - 243,896,003 (+)ENTREZGENERGSC3.4rn4RGSC3.4
Celera1137,119,477 - 137,156,491 (+)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp2c6v1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619934
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.