Gene: Abcb1a (ATP binding cassette subfamily B member 1A) Rattus norvegicus
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Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Description: Predicted to have several functions, including ATPase activity, coupled and lipid transporter activity; involved in several processes, including animal organ development, cellular response to lipid, and response to alkaloid; localizes to the apical plasma membrane and brush border membrane; biomarker of several diseases, including brain disease (multiple), end stage renal failure, hepatocellular carcinoma, human immunodeficiency virus infectious disease, and nonalcoholic fatty liver disease; orthologous to human ABCB1 (ATP binding cassette subfamily B member 1); PARTICIPATES IN clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; docetaxel pharmacodynamics pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (RS)-amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abcb1; ATP binding cassette subfamily B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1A; Mdr1a; multiple drug resistant 1a
Orthologs:
Homo sapiens (human) : ABCB1 (ATP binding cassette subfamily B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Abcb1a (ATP-binding cassette, sub-family B (MDR/TAP), member 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcb1 (ATP binding cassette subfamily B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB1 (ATP binding cassette subfamily B member 1)
Canis lupus familiaris (dog) : ABCB1 (ATP binding cassette subfamily B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb1 (ATP binding cassette subfamily B member 1)
Sus scrofa (pig) : ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)
more info ...
Allele / Splice: Abcb1aem1Sage   Abcb1aem2Sage   Abcb1aem3Sage  
Genetic Models: WI-Abcb1aem2Sage WI-Abcb1aem3Sage SD-Abcb1aem1Sage -/- SD-Abcb1aem1Sage Abcg2em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0422,339,829 - 22,517,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0422,276,390 - 22,448,913 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4421,709,855 - 21,796,628 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1421,709,854 - 21,796,626 (+)NCBI
Celera420,849,575 - 20,934,573 (-)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations