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Gene: Trim63 (tripartite motif containing 63) Rattus norvegicus
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Symbol: Trim63
Name: tripartite motif containing 63
Description: Exhibits ubiquitin-protein transferase activity. Involved in several processes, including regulation of muscle adaptation; response to interleukin-1; and skeletal muscle atrophy. Localizes to the contractile fiber. Biomarker of muscular atrophy. Orthologous to human TRIM63 (tripartite motif containing 63); INTERACTS WITH 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase TRIM63; Murf; MURF-1; Murf1; muscle ring finger protein 1; muscle-specific RING finger protein 1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; Rnf28; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63
Orthologs:
Homo sapiens (human) : TRIM63 (tripartite motif containing 63)  HGNC  Alliance
Mus musculus (house mouse) : Trim63 (tripartite motif-containing 63)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim63 (tripartite motif containing 63)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM63 (tripartite motif containing 63)
Canis lupus familiaris (dog) : TRIM63 (tripartite motif containing 63)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim63 (tripartite motif containing 63)
Sus scrofa (pig) : TRIM63 (tripartite motif containing 63)
more info ...
Allele / Splice: Trim63em1(hiLuc)  
Genetic Models: SD-Trim63em1(hiLuc)/Rrrc
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05152,533,362 - 152,547,138 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05156,292,566 - 156,306,092 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,059,573 - 153,073,907 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15153,069,611 - 153,083,946 (+)NCBI
Celera5144,951,021 - 144,964,729 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Trim63
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619964
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.