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Gene: Stxbp2 (syntaxin binding protein 2) Rattus norvegicus
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Symbol: Stxbp2
Name: syntaxin binding protein 2
Description: Exhibits syntaxin-1 binding activity and syntaxin-3 binding activity. Involved in positive regulation of mast cell degranulation and response to acidic pH. Localizes to several cellular components, including apical plasma membrane; cytoplasm; and lamellipodium. Colocalizes with secretory granule. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 5. Orthologous to human STXBP2 (syntaxin binding protein 2); INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: munc18-2; Munc18b; syntaxin binding protein Munc18-2; syntaxin-binding protein 2; unc-18 homolog 2; unc-18 homolog B; unc-18B; unc18-2
Orthologs:
Homo sapiens (human) : STXBP2 (syntaxin binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Stxbp2 (syntaxin binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stxbp2 (syntaxin binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : STXBP2 (syntaxin binding protein 2)
Canis lupus familiaris (dog) : STXBP2 (syntaxin binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stxbp2 (syntaxin binding protein 2)
Sus scrofa (pig) : STXBP2 (syntaxin binding protein 2)
Chlorocebus sabaeus (African green monkey) : STXBP2 (syntaxin binding protein 2)
Heterocephalus glaber (naked mole-rat) : Stxbp2 (syntaxin binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0122,180,101 - 2,191,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,180,150 - 2,191,175 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,342,202 - 4,353,960 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,511,793 - 2,522,818 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,511,792 - 2,522,818 (-)NCBI
Celera123,545,180 - 3,556,207 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Stxbp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619967
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.