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Gene: Asl (argininosuccinate lyase) Rattus norvegicus
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Symbol: Asl
Name: argininosuccinate lyase
Description: Exhibits argininosuccinate lyase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to organic cyclic compound; and response to peptide hormone. Localizes to several cellular components, including the cell body fiber; cytoplasm; and perikaryon. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and argininosuccinic aciduria. Orthologous to human ASL (argininosuccinate lyase); PARTICIPATES IN urea cycle pathway; AGAT deficiency pathway; arginine and proline metabolic pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arginosuccinase; ASAL
Orthologs:
Homo sapiens (human) : ASL (argininosuccinate lyase)  HGNC  Alliance
Mus musculus (house mouse) : Asl (argininosuccinate lyase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asl (argininosuccinate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ASL (argininosuccinate lyase)
Canis lupus familiaris (dog) : ASL (argininosuccinate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asl (argininosuccinate lyase)
Sus scrofa (pig) : ASL (argininosuccinate lyase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01230,160,922 - 30,178,348 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01232,097,760 - 32,115,110 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,702,882 - 27,720,230 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,570,168 - 27,583,445 (+)NCBI
Celera1228,373,639 - 28,390,987 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Asl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619974
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.