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Gene: Hdac3 (histone deacetylase 3) Rattus norvegicus
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Symbol: Hdac3
Name: histone deacetylase 3
Description: Exhibits several functions, including GTPase binding activity; chromatin binding activity; and deacetylase activity. Contributes to histone deacetylase activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of cytokine production; and positive regulation of apoptotic process. Localizes to the chromatin; cytoplasm; and nucleus. Biomarker of acute kidney failure and impotence. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human HDAC3 (histone deacetylase 3); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HD3
Orthologs:
Homo sapiens (human) : HDAC3 (histone deacetylase 3)  HGNC  Alliance
Mus musculus (house mouse) : Hdac3 (histone deacetylase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac3 (histone deacetylase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC3 (histone deacetylase 3)
Canis lupus familiaris (dog) : HDAC3 (histone deacetylase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac3 (histone deacetylase 3)
Sus scrofa (pig) : HDAC3 (histone deacetylase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01831,073,057 - 31,094,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01830,764,344 - 30,782,387 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,857,209 - 30,875,986 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11830,883,855 - 30,902,632 (-)NCBI
Celera1829,414,681 - 29,434,382 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hdac3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619977
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.