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Gene: Hdac6 (histone deacetylase 6) Rattus norvegicus
Symbol: Hdac6
Name: histone deacetylase 6
Description: Exhibits deacetylase activity. Involved in several processes, including generation of neurons; regulation of protein modification process; and response to glucocorticoid. Localizes to axon and centrosome. Predicted to colocalize with cytoplasmic microtubule and dynein complex. Used to study polycystic kidney disease and polycystic liver disease. Biomarker of hypertension and polycystic liver disease. Orthologous to human HDAC6 (histone deacetylase 6); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone deacetylase 6-like; LOC100911205
Homo sapiens (human) : HDAC6 (histone deacetylase 6)  HGNC  Alliance
Mus musculus (house mouse) : Hdac6 (histone deacetylase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac6 (histone deacetylase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC6 (histone deacetylase 6)
Canis lupus familiaris (dog) : HDAC6 (histone deacetylase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac6 (histone deacetylase 6)
Sus scrofa (pig) : HDAC6 (histone deacetylase 6)
Chlorocebus sabaeus (African green monkey) : HDAC6 (histone deacetylase 6)
Heterocephalus glaber (naked mole-rat) : Hdac6 (histone deacetylase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X15,295,372 - 15,316,673 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,295,473 - 15,316,671 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,075,029 - 16,096,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,585,852 - 26,606,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X26,658,892 - 26,659,565 (+)NCBI
CeleraX14,635,909 - 14,657,201 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Hdac6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619981
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.