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Gene: Mat2a (methionine adenosyltransferase 2A) Rattus norvegicus
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Symbol: Mat2a
Name: methionine adenosyltransferase 2A
Description: Exhibits ATP binding activity; amino acid binding activity; and methionine adenosyltransferase activity. Involved in several processes, including S-adenosylmethionine biosynthetic process; circadian rhythm; and response to cAMP. Localizes to the cytosol. Orthologous to human MAT2A (methionine adenosyltransferase 2A); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adoMet synthase 2; adoMet synthetase 2; MAT 2; MAT-II; methionine adenosyltransferase 2; methionine adenosyltransferase II, alpha; non-hepatic-type S-adenosylmethionine synthetase; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; Sams2
Orthologs:
Homo sapiens (human) : MAT2A (methionine adenosyltransferase 2A)  HGNC  Alliance
Mus musculus (house mouse) : Mat2a (methionine adenosyltransferase II, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mat2a (methionine adenosyltransferase 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : MAT2A (methionine adenosyltransferase 2A)
Canis lupus familiaris (dog) : MAT2A (methionine adenosyltransferase 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mat2a (methionine adenosyltransferase 2A)
Sus scrofa (pig) : MAT2A (methionine adenosyltransferase 2A)
Chlorocebus sabaeus (African green monkey) : MAT2A (methionine adenosyltransferase 2A)
Heterocephalus glaber (naked mole-rat) : Mat2a (methionine adenosyltransferase 2A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04100,297,478 - 100,303,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4100,296,075 - 100,303,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04165,067,990 - 165,073,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,739,943 - 105,745,472 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14105,984,423 - 105,989,953 (-)NCBI
Celera493,642,240 - 93,647,807 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mat2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619985
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.