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Gene: Rims1 (regulating synaptic membrane exocytosis 1) Rattus norvegicus
Symbol: Rims1
Name: regulating synaptic membrane exocytosis 1
Description: Exhibits Rab GTPase binding activity; SH3 domain binding activity; and protein kinase binding activity. Involved in long-term synaptic potentiation; positive regulation of inhibitory postsynaptic potential; and positive regulation of synaptic vesicle priming. Localizes to the glutamatergic synapse; presynaptic active zone cytoplasmic component; and presynaptic membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: rab-3-interacting molecule 1; Rab3 effector; rab3-interacting molecule 1; regulating synaptic membrane exocytosis protein 1; RIM 1; Rim1; RIM1a; Rim1b protein
Homo sapiens (human) : RIMS1 (regulating synaptic membrane exocytosis 1)  HGNC  Alliance
Mus musculus (house mouse) : Rims1 (regulating synaptic membrane exocytosis 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rims1 (regulating synaptic membrane exocytosis 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985164 (regulating synaptic membrane exocytosis protein 1)
Canis lupus familiaris (dog) : RIMS1 (regulating synaptic membrane exocytosis 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rims1 (regulating synaptic membrane exocytosis 1)
Sus scrofa (pig) : RIMS1 (regulating synaptic membrane exocytosis 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0928,440,408 - 28,973,246 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0927,284,845 - 27,813,498 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4921,089,088 - 21,594,679 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1921,090,501 - 21,596,093 (-)NCBI
Celera922,268,968 - 22,762,652 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rims1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620000
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.