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Gene: Rims1 (regulating synaptic membrane exocytosis 1) Rattus norvegicus
Symbol: Rims1
Name: regulating synaptic membrane exocytosis 1
CRRD ID: 620000
Description: Exhibits Rab GTPase binding activity; SH3 domain binding activity; and protein kinase binding activity. Involved in long-term synaptic potentiation; positive regulation of inhibitory postsynaptic potential; and positive regulation of synaptic vesicle priming. Localizes to glutamatergic synapse; presynaptic active zone cytoplasmic component; and presynaptic membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: rab-3-interacting molecule 1; Rab3 effector; rab3-interacting molecule 1; regulating synaptic membrane exocytosis protein 1; RIM 1; Rim1; RIM1a; Rim1b protein
Homo sapiens (human) : RIMS1 (regulating synaptic membrane exocytosis 1)  HGNC  Alliance
Mus musculus (house mouse) : Rims1 (regulating synaptic membrane exocytosis 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rims1 (regulating synaptic membrane exocytosis 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RIMS1 (regulating synaptic membrane exocytosis 1)
Canis lupus familiaris (dog) : RIMS1 (regulating synaptic membrane exocytosis 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rims1 (regulating synaptic membrane exocytosis 1)
Sus scrofa (pig) : RIMS1 (regulating synaptic membrane exocytosis 1)
Chlorocebus sabaeus (African green monkey) : RIMS1 (regulating synaptic membrane exocytosis 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0928,440,408 - 28,973,246 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl928,442,229 - 28,973,246 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0927,284,845 - 27,813,498 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4921,089,088 - 21,594,679 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1921,090,501 - 21,596,093 (-)NCBI
Celera922,268,968 - 22,762,652 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rims1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620000
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.