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Gene: C4a (complement C4A) Rattus norvegicus
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Symbol: C4a
Name: complement C4A
Description: Predicted to have complement component C1q binding activity. Predicted to be involved in complement activation and positive regulation of apoptotic cell clearance. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune hypersensitivity disease (multiple); complement deficiency (multiple); renal cell carcinoma; and rheumatoid arthritis. Orthologous to human C4A (complement C4A (Rodgers blood group)) and C4B (complement C4B (Chido blood group)); PARTICIPATES IN classical complement pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C4; C4-1; C4b; complement C4; complement C4-like; complement component 4 (within H-2S); complement component 4, gene 1; complement component 4a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); complement component 4B (Childo blood group); LOC102549354
Orthologs:
Homo sapiens (human) : C4A (complement C4A (Rodgers blood group))  HGNC  Alliance
Mus musculus (house mouse) : C4a (complement component 4A (Rodgers blood group))  MGI  Alliance
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C4a (complement C4A (Rodgers blood group))
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0202,651,599 - 2,678,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,651,599 - 2,678,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,573,225 - 6,587,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0204,754,468 - 4,755,821 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,106,123 - 4,145,904NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,106,391 - 4,316,103NCBI
Celera204,010,655 - 4,024,973 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on C4a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620005
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.