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Gene: Il12rb1 (interleukin 12 receptor subunit beta 1) Rattus norvegicus
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Symbol: Il12rb1
Name: interleukin 12 receptor subunit beta 1
Description: Predicted to contribute to cytokine receptor activity; interleukin-12 receptor binding activity; and interleukin-23 binding activity. Predicted to be involved in several processes, including cellular response to interferon-gamma; positive regulation of activated T cell proliferation; and positive regulation of defense response to virus by host. Predicted to localize to the external side of plasma membrane; interleukin-12 receptor complex; and interleukin-23 receptor complex. Biomarker of primary biliary cirrhosis. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IL12RB1 (interleukin 12 receptor subunit beta 1); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; diclofenac.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Il12rb; interleukin 12 receptor, beta 1; interleukin-12 receptor subunit beta-1
Orthologs:
Homo sapiens (human) : IL12RB1 (interleukin 12 receptor subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Il12rb1 (interleukin 12 receptor, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Canis lupus familiaris (dog) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Sus scrofa (pig) : IL12RB1 (interleukin 12 receptor subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,370,722 - 20,383,576 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,371,338 - 20,383,337 (-)Ensembl
Rnor_5.01620,227,894 - 20,240,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,126,653 - 19,137,584 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,126,957 - 19,128,305 (-)NCBI
Celera1618,812,772 - 18,825,080 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Il12rb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620025
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.