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Gene: Axl (Axl receptor tyrosine kinase) Rattus norvegicus
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Symbol: Axl
Name: Axl receptor tyrosine kinase
Description: Exhibits myosin heavy chain binding activity and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including animal organ regeneration; cellular response to hydrogen peroxide; and negative regulation of apoptotic process. Predicted to localize to several cellular components, including the cell surface; extracellular space; and host cell surface. Used to study glomerulonephritis. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AXL (AXL receptor tyrosine kinase); PARTICIPATES IN Gas6 - Axl signaling axis; INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC308444; tyrosine-protein kinase receptor UFO
Orthologs:
Homo sapiens (human) : AXL (AXL receptor tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Axl (AXL receptor tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Axl (AXL receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : AXL (AXL receptor tyrosine kinase)
Canis lupus familiaris (dog) : AXL (AXL receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Axl (AXL receptor tyrosine kinase)
Sus scrofa (pig) : AXL (AXL receptor tyrosine kinase)
more info ...
Allele / Splice: Axlem1Mcwi   Axlem2Mcwi  
Genetic Models: SS-Axlem1Mcwi SS-Axlem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0182,550,892 - 82,580,761 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,812,118 - 83,840,542 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,964,751 - 80,994,300 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1181,045,570 - 81,045,733 (-)NCBI
Celera175,705,827 - 75,734,332 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Axl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620028
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.