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Gene: Prdx3 (peroxiredoxin 3) Rattus norvegicus
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Symbol: Prdx3
Name: peroxiredoxin 3
Description: Predicted to have several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein C-terminus binding activity; and thioredoxin peroxidase activity. Involved in negative regulation of neuron apoptotic process. Localizes to the mitochondrion. Biomarker of glucose intolerance. Orthologous to human PRDX3 (peroxiredoxin 3); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1'-azobis(N,N-dimethylformamide); 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: peroxiredoxin-3; PRx III; PRX-3; Prx3; thioredoxin-dependent peroxide reductase, mitochondrial
Orthologs:
Homo sapiens (human) : PRDX3 (peroxiredoxin 3)  HGNC  Alliance
Mus musculus (house mouse) : Prdx3 (peroxiredoxin 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx3 (peroxiredoxin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX3 (peroxiredoxin 3)
Canis lupus familiaris (dog) : PRDX3 (peroxiredoxin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx3 (peroxiredoxin 3)
Sus scrofa (pig) : PRDX3 (peroxiredoxin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01282,238,774 - 282,251,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01289,577,325 - 289,589,744 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41267,468,371 - 267,481,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11267,679,456 - 267,692,358 (-)NCBI
Celera1255,642,701 - 255,655,171 (-)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prdx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620040
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.