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Gene: Prdx4 (peroxiredoxin 4) Rattus norvegicus
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Symbol: Prdx4
Name: peroxiredoxin 4
Description: Predicted to have identical protein binding activity and thioredoxin peroxidase activity. Predicted to be involved in several processes, including cell redox homeostasis; negative regulation of male germ cell proliferation; and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Localizes to extracellular space and smooth endoplasmic reticulum. Orthologous to human PRDX4 (peroxiredoxin 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: antioxidant enzyme AOE372; MGC72744; peroxiredoxin IV; peroxiredoxin-4; prx-IV; thioredoxin peroxidase AO372; thioredoxin-dependent peroxide reductase A0372; thioredoxin-dependent peroxiredoxin 4
Orthologs:
Homo sapiens (human) : PRDX4 (peroxiredoxin 4)  HGNC  Alliance
Mus musculus (house mouse) : Prdx4 (peroxiredoxin 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx4 (peroxiredoxin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX4 (peroxiredoxin 4)
Canis lupus familiaris (dog) : PRDX4 (peroxiredoxin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx4 (peroxiredoxin 4)
Sus scrofa (pig) : PRDX4 (peroxiredoxin 4)
Chlorocebus sabaeus (African green monkey) : PRDX4 (peroxiredoxin 4)
Heterocephalus glaber (naked mole-rat) : Prdx4 (peroxiredoxin 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X43,495,453 - 43,512,994 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX43,497,763 - 43,512,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X43,799,111 - 43,816,649 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X61,501,206 - 61,516,286 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X61,554,679 - 61,569,754 (+)NCBI
CeleraX40,657,785 - 40,672,868 (+)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prdx4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620043
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.