Gene: Pon1 (paraoxonase 1) Rattus norvegicus
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Symbol: Pon1
Name: paraoxonase 1
Description: Exhibits aryldialkylphosphatase activity; involved in several processes, including lipid metabolic process, response to fatty acid, and response to fluoride; localizes to the extracellular space and intracellular membrane-bounded organelle; orthologous to human PON1 (paraoxonase 1); PARTICIPATES IN clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; organophosphate response pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-esterase 1; aromatic esterase 1; PON 1; serum aryldialkylphosphatase 1; serum paraoxonase/arylesterase 1
Orthologs:
Homo sapiens (human) : PON1 (paraoxonase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pon1 (paraoxonase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pon1 (paraoxonase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PON1 (paraoxonase 1)
Canis lupus familiaris (dog) : PON1 (paraoxonase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pon1 (paraoxonase 1)
Sus scrofa (pig) : PON1 (paraoxonase 1)
more info ...
Allele / Splice: Pon1em1Mcwi   Pon1em2Mcwi   Pon1em3Mcwi  
Genetic Models: SS-Pon1em2Mcwi SS-Pon1em3Mcwi SS-Pon1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0430,249,749 - 30,276,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0430,156,712 - 30,183,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4429,936,314 - 29,964,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1429,975,057 - 30,003,299 (-)NCBI
Celera428,821,674 - 28,848,125 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pon1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620062
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.