Gene: Hpgd (15-hydroxyprostaglandin dehydrogenase) Rattus norvegicus
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Symbol: Hpgd
Name: 15-hydroxyprostaglandin dehydrogenase
Description: Exhibits 15-hydroxyprostaglandin dehydrogenase (NAD+) activity and protein homodimerization activity; involved in several processes, including female pregnancy, kidney development, and positive regulation of apoptotic process; localizes to the cytoplasm and extracellular space; used to study carcinoma; biomarker of peptic ulcer disease; orthologous to human HPGD (15-hydroxyprostaglandin dehydrogenase); INTERACTS WITH 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17beta-estradiol; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-hydroxyprostaglandin dehydrogenase [NAD+]; 15-PGDH; hydroxyprostaglandin dehydrogenase 15 (NAD); NAD-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH; prostaglandin dehydrogenase 1
Orthologs:
Homo sapiens (human) : HPGD (15-hydroxyprostaglandin dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Hpgd (hydroxyprostaglandin dehydrogenase 15 (NAD))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpgd (15-hydroxyprostaglandin dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HPGD (15-hydroxyprostaglandin dehydrogenase)
Canis lupus familiaris (dog) : HPGD (15-hydroxyprostaglandin dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgd (15-hydroxyprostaglandin dehydrogenase)
Sus scrofa (pig) : HPGD (15-hydroxyprostaglandin dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01637,457,134 - 37,495,758 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01637,259,044 - 37,296,863 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41637,419,901 - 37,457,896 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11637,419,976 - 37,457,971 (-)NCBI
Celera1633,917,230 - 33,953,504 (-)NCBICelera
Cytogenetic Map16p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hpgd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620087
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.