Gene: Gdf5 (growth differentiation factor 5) Rattus norvegicus
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Symbol: Gdf5
Name: growth differentiation factor 5
Description: Exhibits signaling receptor binding activity; involved in several processes, including negative regulation of neuron apoptotic process, ossification involved in bone remodeling, and positive regulation of neuron differentiation; predicted to localize to the extracellular space; biomarker of Parkinson's disease; orthologous to human GDF5 (growth differentiation factor 5); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: cartilage-derived morphogenetic protein 1; Cdmp1; growth/differentiation factor 5
Orthologs:
Homo sapiens (human) : GDF5 (growth differentiation factor 5)  HGNC  Alliance
Mus musculus (house mouse) : Gdf5 (growth differentiation factor 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf5 (growth differentiation factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF5 (growth differentiation factor 5)
Canis lupus familiaris (dog) : GDF5 (growth differentiation factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf5 (growth differentiation factor 5)
Sus scrofa (pig) : GDF5 (growth differentiation factor 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03151,482,672 - 151,487,129 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03157,849,749 - 157,853,231 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3143,176,803 - 143,181,254 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gdf5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620102
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.