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Gene: Nos1ap (nitric oxide synthase 1 adaptor protein) Rattus norvegicus
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Symbol: Nos1ap
Name: nitric oxide synthase 1 adaptor protein
Description: Exhibits PDZ domain binding activity; nitric-oxide synthase binding activity; and protease binding activity. Involved in several processes, including neuron projection regeneration; positive regulation of peptidyl-cysteine S-nitrosylation; and regulation of high voltage-gated calcium channel activity. Localizes to several cellular components, including glutamatergic synapse; postsynapse; and presynapse. Colocalizes with L-type voltage-gated calcium channel complex; inward rectifier potassium channel complex; and nuclear membrane. Used to study mental depression. Biomarker of congestive heart failure and sciatic neuropathy. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C--terminal PDZ ligand of neuronal nitric oxide synthase protein; C-terminal PDZ domain ligand of neuronal nitric oxide synthase; C-terminal PDZ ligand of neuronal nitric oxide synthase protein; Capon; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; nitric oxide synthase 1 (neuronal) adaptor protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01388,653,123 - 88,943,976 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01393,279,049 - 93,562,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,159,295 - 86,432,815 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11386,173,482 - 86,447,003 (-)NCBI
Celera1382,208,348 - 82,478,185 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nos1ap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620106
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.