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Gene: Ncoa2 (nuclear receptor coactivator 2) Rattus norvegicus
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Symbol: Ncoa2
Name: nuclear receptor coactivator 2
Description: Exhibits DNA polymerase binding activity; PDZ domain binding activity; and nuclear hormone receptor binding activity. Involved in several processes, including male gonad development; positive regulation of female receptivity; and positive regulation of glucocorticoid receptor signaling pathway. Localizes to several cellular components, including the dendritic spine; postsynaptic density; and rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NCOA2 (nuclear receptor coactivator 2); PARTICIPATES IN aldosterone signaling pathway; altered androgen signaling pathway; androgen signaling pathway; INTERACTS WITH (+)-schisandrin B; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NCoA-2; Tif2; transcriptional intermediary factor 2
Orthologs:
Homo sapiens (human) : NCOA2 (nuclear receptor coactivator 2)  HGNC  Alliance
Mus musculus (house mouse) : Ncoa2 (nuclear receptor coactivator 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa2 (nuclear receptor coactivator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA2 (nuclear receptor coactivator 2)
Canis lupus familiaris (dog) : NCOA2 (nuclear receptor coactivator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa2 (nuclear receptor coactivator 2)
Sus scrofa (pig) : NCOA2 (nuclear receptor coactivator 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.055,466,544 - 5,696,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl55,616,483 - 5,694,598 (+)Ensembl
Rnor_5.0510,306,581 - 10,538,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.455,197,891 - 5,275,776 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.155,197,890 - 5,273,000 (+)NCBI
Celera55,570,901 - 5,648,759 (+)NCBICelera
Cytogenetic Map5q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ncoa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620108
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.