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Gene: Ncoa3 (nuclear receptor coactivator 3) Rattus norvegicus
Symbol: Ncoa3
Name: nuclear receptor coactivator 3
Description: Exhibits several functions, including nuclear receptor transcription coactivator activity; peroxisome proliferator activated receptor binding activity; and steroid hormone receptor binding activity. Involved in several processes, including male gonad development; positive regulation of intracellular estrogen receptor signaling pathway; and regulation of transcription, DNA-templated. Localizes to Golgi apparatus; nucleus; and perinuclear region of cytoplasm. Used to study breast cancer. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NCOA3 (nuclear receptor coactivator 3); PARTICIPATES IN androgen signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AIB-1; Aib1; amplified in breast cancer-1 protein homolog; NCoA-3; thyroid hormone receptor activator molecule 1; Tram-1
Homo sapiens (human) : NCOA3 (nuclear receptor coactivator 3)  HGNC  Alliance
Mus musculus (house mouse) : Ncoa3 (nuclear receptor coactivator 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa3 (nuclear receptor coactivator 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA3 (nuclear receptor coactivator 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa3 (nuclear receptor coactivator 3)
Sus scrofa (pig) : NCOA3 (nuclear receptor coactivator 3)
Chlorocebus sabaeus (African green monkey) : NCOA3 (nuclear receptor coactivator 3)
Heterocephalus glaber (naked mole-rat) : Ncoa3 (nuclear receptor coactivator 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03162,692,176 - 162,788,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3162,692,185 - 162,787,548 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03168,863,837 - 168,959,427 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43157,168,492 - 157,196,566 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13157,079,533 - 157,100,362 (+)NCBI
Celera3153,323,587 - 153,406,335 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ncoa3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620109
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.