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Gene: Ap2m1 (adaptor related protein complex 2 subunit mu 1) Rattus norvegicus
Symbol: Ap2m1
Name: adaptor related protein complex 2 subunit mu 1
Description: Exhibits cargo receptor activity; low-density lipoprotein particle receptor binding activity; and signal sequence binding activity. Involved in positive regulation of endocytosis; protein-containing complex assembly; and vesicle-mediated transport in synapse. Localizes to the AP-2 adaptor complex and glutamatergic synapse. Orthologous to human AP2M1 (adaptor related protein complex 2 subunit mu 1); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.
Type: protein-coding
Also known as: adapter-related protein complex 2 mu subunit; adapter-related protein complex 2 subunit mu; adaptor protein complex AP-2 subunit mu; adaptor-related protein complex 2 subunit mu; adaptor-related protein complex 2, mu 1 subunit; AP-2 complex subunit mu; AP-2 mu chain; Ap50; Clapm1; clathrin assembly protein complex 2 medium chain; clathrin assembly protein complex 2 mu medium chain; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; coat assembly protein complex 50 kD; coat assembly protein complex, 50 kD; MGC105352; mu2; mu2-adaptin; plasma membrane adaptor AP-2 50 kDa protein
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01184,041,184 - 84,047,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01187,113,496 - 87,119,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,585,474 - 82,591,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11182,643,062 - 82,649,421 (-)NCBI
Celera1179,194,852 - 79,201,210 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ap2m1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620135
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.