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Gene: Pkn2 (protein kinase N2) Rattus norvegicus
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Symbol: Pkn2
Name: protein kinase N2
Description: Exhibits protein serine/threonine kinase activity. Predicted to be involved in several processes, including apical junction assembly; positive regulation of cell cycle; and positive regulation of viral genome replication. Predicted to localize to several cellular components, including the cleavage furrow; cytoskeleton; and midbody. Orthologous to human PKN2 (protein kinase N2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cardiolipin-activated protein kinase Pak2; p140 kinase; Pak-2; PKN gamma; Prkcl2; protease-activated kinase 2; protein kinase C-like 2; protein-kinase C-related kinase 2; serine/threonine-protein kinase N2; similar to human PRKCL2 (protein kinase C-like 2)
Orthologs:
Homo sapiens (human) : PKN2 (protein kinase N2)  HGNC  Alliance
Mus musculus (house mouse) : Pkn2 (protein kinase N2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pkn2 (protein kinase N2)
Pan paniscus (bonobo/pygmy chimpanzee) : PKN2 (protein kinase N2)
Canis lupus familiaris (dog) : PKN2 (protein kinase N2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pkn2 (protein kinase N2)
Sus scrofa (pig) : PKN2 (protein kinase N2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02248,735,699 - 248,840,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2248,735,699 - 248,840,735 (-)Ensembl
Rnor_5.02267,265,825 - 267,370,861 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42240,903,608 - 241,009,063 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12240,892,652 - 240,944,091 (-)NCBI
Celera2223,803,766 - 223,906,746 (-)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pkn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620146
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.