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Gene: Mmp13 (matrix metallopeptidase 13) Rattus norvegicus
Symbol: Mmp13
Name: matrix metallopeptidase 13
Description: Exhibits several functions, including fibronectin binding activity; low-density lipoprotein particle receptor binding activity; and metal ion binding activity. Involved in several processes, including animal organ development; embryonic hindlimb morphogenesis; and estrous cycle. Localizes to several cellular components, including Golgi apparatus; intercellular canaliculus; and lysosome. Used to study brain ischemia; degenerative disc disease; and myocardial infarction. Biomarker of several diseases, including bone disease (multiple); gastric ulcer; liver cirrhosis (multiple); meningococcal meningitis; and silicosis. Human ortholog(s) of this gene implicated in anodontia; artery disease (multiple); bone disease (multiple); and ovarian carcinoma. Orthologous to human MMP13 (matrix metallopeptidase 13); INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: collagenase 3; collagenase-3; interstitial collagenase; matrix metalloproteinase 13; matrix metalloproteinase-13; MMP-13; UMRCASE
Homo sapiens (human) : MMP13 (matrix metallopeptidase 13)  HGNC  Alliance
Mus musculus (house mouse) : Mmp13 (matrix metallopeptidase 13)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp13 (matrix metallopeptidase 13)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP13 (matrix metallopeptidase 13)
Canis lupus familiaris (dog) : MMP13 (matrix metallopeptidase 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp13 (matrix metallopeptidase 13)
Sus scrofa (pig) : MMP13 (matrix metallopeptidase 13)
Chlorocebus sabaeus (African green monkey) : MMP13 (matrix metallopeptidase 13)
Heterocephalus glaber (naked mole-rat) : Mmp13 (matrix metallopeptidase 13)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.085,522,739 - 5,533,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,522,739 - 5,533,018 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,527,980 - 5,538,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,158,887 - 4,169,166 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.184,158,913 - 4,169,165 (+)NCBI
Celera86,061,454 - 6,071,733 (+)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mmp13
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620196
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.