Gene: Mmp14 (matrix metallopeptidase 14) Rattus norvegicus
Analyze
Symbol: Mmp14
Name: matrix metallopeptidase 14
Description: Exhibits integrin binding activity; involved in several processes, including angiogenesis, astrocyte cell migration, and development of primary sexual characteristics; localizes to the cytoplasm; used to study ischemia; biomarker of IgA glomerulonephritis, anti-basement membrane glomerulonephritis, artery disease (multiple), brain ischemia, and congestive heart failure; orthologous to human MMP14 (matrix metallopeptidase 14); PARTICIPATES IN hypoxia inducible factor pathway; gonadotropin-releasing hormone signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: matrix metallopeptidase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase 14 membrane-inserted; matrix metalloproteinase 14, membrane-inserted; matrix metalloproteinase-14; membrane type 1-matrix metalloproteinase; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-14; MT-MMP 1; Mt1-mmp; MT1MMP; MTMMP1
Orthologs:
Homo sapiens (human) : MMP14 (matrix metallopeptidase 14)  HGNC  Alliance
Mus musculus (house mouse) : Mmp14 (matrix metallopeptidase 14 (membrane-inserted))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp14 (matrix metallopeptidase 14)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP14 (matrix metallopeptidase 14)
Canis lupus familiaris (dog) : MMP14 (matrix metallopeptidase 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp14 (matrix metallopeptidase 14)
Sus scrofa (pig) : MMP14 (matrix metallopeptidase 14)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01533,074,441 - 33,083,666 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01536,960,282 - 36,969,507 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,493,852 - 32,503,077 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11532,509,551 - 32,518,777 (+)NCBI
Celera1527,470,861 - 27,480,086 (+)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mmp14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620198
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-05-14
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.