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Gene: Acvr1 (activin A receptor type 1) Rattus norvegicus
Symbol: Acvr1
Name: activin A receptor type 1
Description: Exhibits activin receptor activity, type I. Involved in several processes, including cellular response to glucocorticoid stimulus; regulation of skeletal muscle tissue development; and transforming growth factor beta receptor signaling pathway. Localizes to activin receptor complex. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1); PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
Also known as: activin A receptor, type 1; activin A receptor, type I; activin receptor type I; activin receptor type-1; activin type I receptor; ACTR-I; ALK2-B; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TSR-I
Homo sapiens (human) : ACVR1 (activin A receptor type 1)  HGNC  Alliance
Mus musculus (house mouse) : Acvr1 (activin A receptor, type 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr1 (activin A receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR1 (activin A receptor type 1)
Canis lupus familiaris (dog) : ACVR1 (activin A receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr1 (activin A receptor type 1)
Sus scrofa (pig) : ACVR1 (activin A receptor type 1)
Chlorocebus sabaeus (African green monkey) : ACVR1 (activin A receptor type 1)
Heterocephalus glaber (naked mole-rat) : Acvr1 (activin A receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0344,432,476 - 44,539,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl344,432,471 - 44,522,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0349,551,411 - 49,641,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,191,727 - 40,260,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,088,098 - 40,156,860 (-)NCBI
Celera341,046,965 - 41,113,654 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acvr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620200
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.