Gene: Ppat (phosphoribosyl pyrophosphate amidotransferase) Rattus norvegicus
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Symbol: Ppat
Name: phosphoribosyl pyrophosphate amidotransferase
Description: Exhibits amidophosphoribosyltransferase activity; involved in several processes, including G1/S transition of mitotic cell cycle, animal organ development, and cellular response to drug; biomarker of hepatocellular carcinoma and renal cell carcinoma; orthologous to human PPAT (phosphoribosyl pyrophosphate amidotransferase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amidophosphoribosyltransferase; Atase; glutamine phosphoribosylpyrophosphate amidotransferase; GPAT; MGC93251
Orthologs:
Homo sapiens (human) : PPAT (phosphoribosyl pyrophosphate amidotransferase)  HGNC  Alliance
Mus musculus (house mouse) : Ppat (phosphoribosyl pyrophosphate amidotransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppat (phosphoribosyl pyrophosphate amidotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : PPAT (phosphoribosyl pyrophosphate amidotransferase)
Canis lupus familiaris (dog) : PPAT (phosphoribosyl pyrophosphate amidotransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppat (phosphoribosyl pyrophosphate amidotransferase)
Sus scrofa (pig) : PPAT (phosphoribosyl pyrophosphate amidotransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01433,580,541 - 33,614,919 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01433,371,454 - 33,405,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41433,509,364 - 33,543,743 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11433,509,363 - 33,543,743 (+)NCBI
Celera1430,529,492 - 30,563,868 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ppat
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620237
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.