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Gene: Abca2 (ATP binding cassette subfamily A member 2) Rattus norvegicus
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Symbol: Abca2
Name: ATP binding cassette subfamily A member 2
Description: Exhibits ATP binding activity. Involved in negative regulation of lipid metabolic process; negative regulation of low-density lipoprotein receptor activity; and positive regulation of amyloid-beta formation. Localizes to the cytoplasmic vesicle and microtubule organizing center. Orthologous to human ABCA2 (ATP binding cassette subfamily A member 2); INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abc2; ATP-binding cassette 2; ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette, sub-family A (ABC1), member 2; ATP-binding cassette, subfamily A (ABC1), member 2
Orthologs:
Homo sapiens (human) : ABCA2 (ATP binding cassette subfamily A member 2)  HGNC  Alliance
Mus musculus (house mouse) : Abca2 (ATP-binding cassette, sub-family A (ABC1), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abca2 (ATP binding cassette subfamily A member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA2 (ATP binding cassette subfamily A member 2)
Canis lupus familiaris (dog) : ABCA2 (ATP binding cassette subfamily A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abca2 (ATP binding cassette subfamily A member 2)
Sus scrofa (pig) : ABCA2 (ATP binding cassette subfamily A member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.032,648,787 - 2,668,770 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,648,885 - 2,668,809 (+)Ensembl
Rnor_5.032,630,237 - 2,650,183 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,595,423 - 3,615,328 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.133,595,422 - 3,615,327 (+)NCBI
Celera33,069,743 - 3,089,646 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abca2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620238
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.