Gene: P2rx3 (purinergic receptor P2X 3) Rattus norvegicus
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Symbol: P2rx3
Name: purinergic receptor P2X 3
Description: Exhibits ATP binding activity, extracellularly ATP-gated cation channel activity, and purinergic nucleotide receptor activity; involved in several processes, including behavioral response to formalin induced pain, cellular response to ATP, and neuronal action potential; localizes to several cellular components, including the cytoplasm, integral component of presynaptic membrane, and neuron projection; orthologous to human P2RX3 (purinergic receptor P2X 3); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; P2X purinoceptor 3; P2X3; purinergic receptor P2X ligand-gated ion channel, 3; purinergic receptor P2X, ligand-gated ion channel, 3
Orthologs:
Homo sapiens (human) : P2RX3 (purinergic receptor P2X 3)  HGNC  Alliance
Mus musculus (house mouse) : P2rx3 (purinergic receptor P2X, ligand-gated ion channel, 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx3 (purinergic receptor P2X 3)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX3 (purinergic receptor P2X 3)
Canis lupus familiaris (dog) : P2RX3 (purinergic receptor P2X 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx3 (purinergic receptor P2X 3)
Sus scrofa (pig) : P2RX3 (purinergic receptor P2X 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0372,403,992 - 72,447,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0378,914,029 - 78,958,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,228,045 - 68,270,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1368,124,416 - 68,167,123 (-)NCBI
Celera369,431,850 - 69,475,670 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on P2rx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620253
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.