Gene: Gli3 (GLI family zinc finger 3) Rattus norvegicus
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Symbol: Gli3
Name: GLI family zinc finger 3
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and enzyme binding activity; involved in animal organ development, response to estrogen, and wound healing; localizes to the cytoplasm and nucleus; biomarker of clubfoot and hypospadias; orthologous to human GLI3 (GLI family zinc finger 3); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; pancreatic cancer pathway; INTERACTS WITH 17beta-estradiol; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GLI-Kruppel family member GLI3; GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome); LOC307001; transcriptional activator GLI3
Orthologs:
Homo sapiens (human) : GLI3 (GLI family zinc finger 3)  HGNC  Alliance
Mus musculus (house mouse) : Gli3 (GLI-Kruppel family member GLI3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gli3 (GLI family zinc finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GLI3 (GLI family zinc finger 3)
Canis lupus familiaris (dog) : GLI3 (GLI family zinc finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gli3 (GLI family zinc finger 3)
Sus scrofa (pig) : GLI3 (GLI family zinc finger 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01752,294,942 - 52,569,036 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01750,360,049 - 50,629,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41757,594,102 - 57,867,710 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11757,781,069 - 57,856,545 (-)NCBI
Celera1745,497,321 - 45,768,089 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gli3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620272
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.