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Gene: Nr0b1 (nuclear receptor subfamily 0, group B, member 1) Rattus norvegicus
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Symbol: Nr0b1
Name: nuclear receptor subfamily 0, group B, member 1
Description: Exhibits double-stranded DNA binding activity and sequence-specific DNA binding activity. Involved in regulation of transcription, DNA-templated; response to peptide hormone; and spermatogenesis. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in 46,XY sex reversal 2 and X-linked adrenal hypoplasia congenita. Orthologous to human NR0B1 (nuclear receptor subfamily 0 group B member 1); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adrenal hypoplasia congenital homolog (human); adrenal hypoplasia, congenital homolog; Ahch; DAX-1; nuclear receptor DAX-1; nuclear receptor subfamily 0 group B member 1
Orthologs:
Homo sapiens (human) : NR0B1 (nuclear receptor subfamily 0 group B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Nr0b1 (nuclear receptor subfamily 0, group B, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Canis lupus familiaris (dog) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
Sus scrofa (pig) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Chlorocebus sabaeus (African green monkey) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Heterocephalus glaber (naked mole-rat) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X54,734,385 - 54,738,513 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,734,385 - 54,738,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X54,937,819 - 54,941,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X73,006,294 - 73,010,422 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X73,079,585 - 73,083,711 (+)NCBI
CeleraX51,292,676 - 51,296,804 (+)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr0b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62028
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.