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Gene: Myh6 (myosin heavy chain 6) Rattus norvegicus
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Symbol: Myh6
Name: myosin heavy chain 6
Description: Exhibits ATP binding activity; identical protein binding activity; and nucleoside-triphosphatase activity. Involved in several processes, including cellular response to 3,3',5-triiodo-L-thyronine; muscle contraction; and response to heat. Localizes to mitochondrion; muscle myosin complex; and myofibril. Biomarker of congestive heart failure; hypothyroidism; and myocardial infarction. Human ortholog(s) of this gene implicated in atrial heart septal defect (multiple); heart conduction disease (multiple); and intrinsic cardiomyopathy (multiple). Orthologous to human MYH6 (myosin heavy chain 6); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; myocarditis pathway; INTERACTS WITH (R)-noradrenaline; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Myh7; myHC-alpha; MyHC-beta; MyHC-slow; Myhca; Myosin heavy chain 7; myosin heavy chain cardiac muscle adult; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain polypeptide 6 cardiac muscle alpha; myosin heavy chain, cardiac muscle alpha isoform; myosin heavy chain, polypeptide 6; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin-6; Myosin-7
Orthologs:
Homo sapiens (human) : MYH6 (myosin heavy chain 6)  HGNC  Alliance
Mus musculus (house mouse) : Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MYH6 (myosin heavy chain 6)
Canis lupus familiaris (dog) : MYH6 (myosin heavy chain 6)
Chlorocebus sabaeus (African green monkey) : MYH6 (myosin heavy chain 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01533,605,653 - 33,629,730 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,605,654 - 33,629,699 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,492,599 - 37,516,786 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,044,506 - 33,068,098 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,060,206 - 33,083,798 (-)NCBI
Celera1527,995,918 - 28,019,393 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Myh6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62029
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.