Gene: Ereg (epiregulin) Rattus norvegicus
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Symbol: Ereg
Name: epiregulin
Description: Exhibits growth factor activity; involved in several processes, including gamete generation, luteinizing hormone signaling pathway, and positive regulation of cellular metabolic process; localizes to the extracellular space; orthologous to human EREG (epiregulin); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epiregulin precursor; proepiregulin
Orthologs:
Homo sapiens (human) : EREG (epiregulin)  HGNC  Alliance
Mus musculus (house mouse) : Ereg (epiregulin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ereg (epiregulin)
Pan paniscus (bonobo/pygmy chimpanzee) : EREG (epiregulin)
Canis lupus familiaris (dog) : EREG (epiregulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ereg (epiregulin)
Sus scrofa (pig) : EREG (epiregulin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01418,577,620 - 18,591,395 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01418,486,956 - 18,500,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,521,069 - 18,534,844 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11418,521,068 - 18,534,844 (-)NCBI
Celera1416,405,096 - 16,418,803 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ereg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620299
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.