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Gene: Pdpk1 (3-phosphoinositide dependent protein kinase-1) Rattus norvegicus
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Symbol: Pdpk1
Name: 3-phosphoinositide dependent protein kinase-1
Description: Exhibits 3-phosphoinositide-dependent protein kinase activity; insulin receptor binding activity; and protein kinase binding activity. Involved in cellular response to brain-derived neurotrophic factor stimulus; focal adhesion assembly; and negative regulation of neuron apoptotic process. Localizes to cytosol; perikaryon; and plasma membrane. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to several human genes including PDPK1 (3-phosphoinositide dependent protein kinase 1); PARTICIPATES IN angiotensin II signaling pathway; adenosine signaling pathway; FasL mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-phosphoinositide-dependent protein kinase 1; pkB kinase; protein kinase B kinase
Orthologs:
Homo sapiens (human) : PDPK1 (3-phosphoinositide dependent protein kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pdpk1 (3-phosphoinositide dependent protein kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdpk1 (3-phosphoinositide dependent protein kinase 1)
Canis lupus familiaris (dog) : PDPK1 (3-phosphoinositide dependent protein kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdpk1 (3-phosphoinositide dependent protein kinase 1)
Sus scrofa (pig) : PDPK1 (3-phosphoinositide dependent protein kinase 1)
Chlorocebus sabaeus (African green monkey) : PDPK1 (3-phosphoinositide dependent protein kinase 1)
Heterocephalus glaber (naked mole-rat) : Pdpk1 (3-phosphoinositide dependent protein kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01013,446,373 - 13,525,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,451,624 - 13,515,448 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,262,177 - 13,339,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,329,708 - 13,394,080 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,329,707 - 13,394,080 (-)NCBI
Celera1012,796,598 - 12,860,647 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pdpk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620307
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.