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Gene: Npff (neuropeptide FF-amide peptide precursor) Rattus norvegicus
Symbol: Npff
Name: neuropeptide FF-amide peptide precursor
Description: Exhibits G protein-coupled receptor binding activity and neuropeptide hormone activity. Involved in several processes, including ion homeostasis; negative regulation of insulin secretion; and peptide hormone secretion. Localizes to several cellular components, including the axon terminus; dendrite; and perikaryon. Orthologous to human NPFF (neuropeptide FF-amide peptide precursor); INTERACTS WITH bisphenol A; endosulfan; indole-3-methanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FMRFamide-related peptides; pro-FMRFamide-related neuropeptide FF
Homo sapiens (human) : NPFF (neuropeptide FF-amide peptide precursor)  HGNC  Alliance
Mus musculus (house mouse) : Npff (neuropeptide FF-amide peptide precursor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npff (neuropeptide FF-amide peptide precursor)
Pan paniscus (bonobo/pygmy chimpanzee) : NPFF (neuropeptide FF-amide peptide precursor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npff (neuropeptide FF-amide peptide precursor)
Sus scrofa (pig) : NPFF (neuropeptide FF-amide peptide precursor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07144,127,084 - 144,127,873 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07141,919,079 - 141,919,868 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7130,082,133 - 130,082,891 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Npff
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62033
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.