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Gene: Slc1a6 (solute carrier family 1 member 6) Rattus norvegicus
Symbol: Slc1a6
Name: solute carrier family 1 member 6
Description: Exhibits high-affinity glutamate transmembrane transporter activity. Involved in L-glutamate import across plasma membrane. Localizes to integral component of postsynaptic membrane; membrane protein complex; and parallel fiber to Purkinje cell synapse. Orthologous to human SLC1A6 (solute carrier family 1 member 6); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
Also known as: EAAT4; excitatory amino acid transporter 4; high affinity aspartate/glutamate transporter; high-affinity neuronal glutamate transporter; MGC114297; sodium-dependent glutamate/aspartate transporter; solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Homo sapiens (human) : SLC1A6 (solute carrier family 1 member 6)  HGNC  Alliance
Mus musculus (house mouse) : Slc1a6 (solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc1a6 (solute carrier family 1 member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC1A6 (solute carrier family 1 member 6)
Canis lupus familiaris (dog) : SLC1A6 (solute carrier family 1 member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc1a6 (solute carrier family 1 member 6)
Sus scrofa (pig) : SLC1A6 (solute carrier family 1 member 6)
Chlorocebus sabaeus (African green monkey) : SLC1A6 (solute carrier family 1 member 6)
Heterocephalus glaber (naked mole-rat) : Slc1a6 (solute carrier family 1 member 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0713,730,101 - 13,758,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,730,253 - 13,751,271 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,893,841 - 13,921,839 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,393,284 - 12,419,893 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1712,393,284 - 12,419,880 (-)NCBI
Celera78,958,917 - 8,988,056 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Slc1a6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620340
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.